Whole Exome Sequencing vs Whole Genome Sequencing: What’s the Difference? by arovedalc Published: June 10, 2026 (1 month ago) Category Health and Beauty Link Whole Exome Sequencing vs Whole Genome Sequencing If you’ve been exploring advanced genetic testing, you’ve likely come across two terms that sound similar but serve different purposes, Whole Exome Sequencing (WES) and Whole Genome Sequencing (WGS).